[gmx-users] How to install a new Forcefield in Gromacs 4.5.3

Qin Qiao qiaoqin47 at gmail.com
Fri Jan 21 03:17:07 CET 2011


2011/1/21 Justin A. Lemkul <jalemkul at vt.edu>

>
>
> Qin Qiao wrote:
>
>>
>>
>> 2011/1/20 Justin A. Lemkul <jalemkul at vt.edu <mailto:jalemkul at vt.edu>>
>>
>>
>>
>>    Qin Qiao wrote:
>>
>>
>>
>>        2011/1/20 Justin A. Lemkul <jalemkul at vt.edu
>>        <mailto:jalemkul at vt.edu> <mailto:jalemkul at vt.edu
>>        <mailto:jalemkul at vt.edu>>>
>>
>>
>>
>>           Qin Qiao wrote:
>>
>>
>>
>>               2011/1/20 Justin A. Lemkul <jalemkul at vt.edu
>>        <mailto:jalemkul at vt.edu>
>>               <mailto:jalemkul at vt.edu <mailto:jalemkul at vt.edu>>
>>        <mailto:jalemkul at vt.edu <mailto:jalemkul at vt.edu>
>>
>>               <mailto:jalemkul at vt.edu <mailto:jalemkul at vt.edu>>>>
>>
>>
>>
>>
>>
>>                  Qin Qiao wrote:
>>
>>                      Dear all,
>>
>>                      I would like to try a new forcefield in Gromacs
>>        4.5.3. What
>>                      should I do after I copied the ff to
>>        /share/gromacs/top
>>                      directory? It seems the original FF.dat doesn't
>>        exist in
>>               4.5.3..
>>                      Could you give me some help?
>>
>>
>>                  pdb2gmx detects forcefield directories by searching
>>        for names
>>               that
>>                  end in .ff, then looking in that directory for a
>>        "forcefield.doc"
>>                  file that contains a brief description of the force
>> field.
>>
>>                  -Justin
>>
>>
>>               Thanks. But I cannot find the new forcefield when I used
>>               pdb2gmx.. the folder of ff is named 'PACE.ff'
>>
>>
>>           It must also contain a forcefield.itp file to be recognized, and
>>           ultimately, to work at all.  I did a test of minimum
>>        requirements,
>>           and only after I added a dummy forcefield.itp file to the
>> test.ff
>>           subdirectory did pdb2gmx recognize the new force field.
>>
>>           -Justin
>>
>>
>>        There is an .itp file in the ff.. but it doesn't work..
>>        strange.. is there any other possibility?
>>
>>
>>    It works just fine for me.  To be sure, I used the name "PACE.ff"
>>    instead of my generic "test.ff" to make sure capitalization or
>>    something foolish wasn't a problem.  It worked fine, adding "PACE"
>>    as entry 16 in the pdb2gmx menu (I also have another custom force
>>    field, so the order of your pdb2gmx output may be different).
>>
>>    The other thing to try is to build the force field in your working
>>    directory and see if pdb2gmx finds it there.  This is, of course,
>>    not strictly required (and would be very inconvenient), but it could
>>    be a useful diagnostic.
>>
>>    -Justin
>>
>>
>> Thanks. But it doesn't work.. and I tried to copy the exact files in the
>> charmm.ff to a new test.ff, and pdb2gmx doesn't find test.ff..
>>
>>
> Do you have multiple versions of Gromacs on the same machine?  If so, are
> you calling the right pdb2gmx?
>
> Could you tell me how can I tell which version of pdb2gmx I call?


-Justin
>
>
>
>>                      Best,
>>
>>                      Qin
>>
>>
>>                  --     ========================================
>>
>>                  Justin A. Lemkul
>>                  Ph.D. Candidate
>>                  ICTAS Doctoral Scholar
>>                  MILES-IGERT Trainee
>>                  Department of Biochemistry
>>                  Virginia Tech
>>                  Blacksburg, VA
>>                  jalemkul[at]vt.edu <http://vt.edu> <http://vt.edu>
>>        <http://vt.edu> | (540)
>>
>>               231-9080
>>
>>                  http://www.bevanlab.biochem.vt.edu/Pages/Personal/justin
>>
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>>           --     ========================================
>>
>>           Justin A. Lemkul
>>           Ph.D. Candidate
>>           ICTAS Doctoral Scholar
>>           MILES-IGERT Trainee
>>           Department of Biochemistry
>>           Virginia Tech
>>           Blacksburg, VA
>>           jalemkul[at]vt.edu <http://vt.edu> <http://vt.edu> | (540)
>>        231-9080
>>           http://www.bevanlab.biochem.vt.edu/Pages/Personal/justin
>>
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>>    --     ========================================
>>
>>    Justin A. Lemkul
>>    Ph.D. Candidate
>>    ICTAS Doctoral Scholar
>>    MILES-IGERT Trainee
>>    Department of Biochemistry
>>    Virginia Tech
>>    Blacksburg, VA
>>    jalemkul[at]vt.edu <http://vt.edu> | (540) 231-9080
>>    http://www.bevanlab.biochem.vt.edu/Pages/Personal/justin
>>
>>    ========================================
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> --
> ========================================
>
> Justin A. Lemkul
> Ph.D. Candidate
> ICTAS Doctoral Scholar
> MILES-IGERT Trainee
> Department of Biochemistry
> Virginia Tech
> Blacksburg, VA
> jalemkul[at]vt.edu | (540) 231-9080
> http://www.bevanlab.biochem.vt.edu/Pages/Personal/justin
>
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