[gmx-users] monomer to dimer

[Justin Lemkul]

On 9/21/12 10:49 AM, Hossein Lanjanian wrote:
> Dear all
> I want to simulate insulin receptor in plasma membrane. The monomer form of
> receptor, that has 1382 amino acid, is available in Uniprot database. But I
> need dimer form of it.
> question: How can I prepare a pdb file of dimer? Is there any better
> suggestion instead of manipulating pdb file of monomer?
>

If there is no available structure for the dimer, then you need to produce one 
based on any and all available experimental evidence for how two monomers may 
interact.

-Justin

-- 
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Justin A. Lemkul, Ph.D.
Research Scientist
Department of Biochemistry
Virginia Tech
Blacksburg, VA
jalemkul[at]vt.edu | (540) 231-9080
http://www.bevanlab.biochem.vt.edu/Pages/Personal/justin

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