[gmx-users] Invalid order for directive atomtypes

Daniele Veclani danieleveclani at gmail.com
Mon Sep 21 14:53:12 CEST 2015


Dear Justin.

Thanks for you quick answer,

I checked the your suggested link.

But I have that both molecules (solvent and solute) introduce new atoms
types.

How can I do??

best regard
D.V.

2015-09-21 14:15 GMT+02:00 Justin Lemkul <jalemkul at vt.edu>:

>
>
> On 9/21/15 8:06 AM, Daniele Veclani wrote:
>
>> Dear Gromacs Useres
>>
>> I'm trying to study a molecule in methanol (I have already studied this
>> molecule in water) with charmm27 force field.
>>
>> I created the file .itp for methanol (solvent):
>>
>> [ atomtypes ]
>> ; name at.num  mass   charge  ptype    sigma            epsilon
>> CR      6   12.0110  0.0  A         0.387541    0.230120
>> HCMM    1    1.0079  0.0  A         0.235197    0.092048
>> OR      8   15.9994  0.0  A         0.315378    0.636386
>> HOR     1    1.0079  0.0  A         0.040001    0.192464
>>
>>
>> [ pairtypes ]
>> ;  i     j    func     sigma1-4       epsilon1-4 ; THESE ARE 1-4
>> INTERACTIONS
>> CR       CR     1      0.338541    0.041840
>> CR       HCMM   1      0.286869    0.062059
>> CR       OR     1      0.326960    0.163176
>> CR       HOR    1      0.189271    0.089737
>>
>> [ moleculetype ]
>> ; Name nrexcl
>> SOL     3
>>
>> [ atoms ]
>> ; nr type resnr resid atom cgnr charge mass
>>     1 CR   1  SOL C       1  0.2800  12.0110
>>     2 HCMM 1  SOL H       2  0.0000   1.0079
>>     3 HCMM 1  SOL H1      3  0.0000   1.0079
>>     4 HCMM 1  SOL H2      4  0.0000   1.0079
>>     5 OR   1  SOL O       5 -0.6800  15.9994
>>     6 HOR  1  SOL H3      6  0.4000   1.0079
>>
>> [ bonds ]
>> ; ai aj fu b0 kb, b0 kb
>>    5   6 1 0.09720  469365.3  0.09720  469365.3
>>    5   1 1 0.14180  303937.5  0.14180  303937.5
>>    2   1 1 0.10930  287014.9  0.10930  287014.9
>>    1   4 1 0.10930  287014.9  0.10930  287014.9
>>    1   3 1 0.10930  287014.9  0.10930  287014.9
>>
>> [ pairs ]
>> ; ai aj fu
>>    2   6 1
>>    3   6 1
>>    4   6 1
>>
>> [ angles ]
>> ; ai aj ak fu th0 kth ub0 kub th0 kth ub0 kub
>>    2   1   3 1  108.8360  310.74    108.8360  310.74
>>    2   1   4 1  108.8360  310.74    108.8360  310.74
>>    2   1   5 1  108.5770  470.32    108.5770  470.32
>>    3   1   4 1  108.8360  310.74    108.8360  310.74
>>    3   1   5 1  108.5770  470.32    108.5770  470.32
>>    4   1   5 1  108.5770  470.32    108.5770  470.32
>>    1   5   6 1  106.5030  477.55    106.5030  477.55
>>
>> [ dihedrals ]
>> ; ai aj ak al fu phi0 kphi mult phi0 kphi mult
>>    2   1   5   6 9   0.00   1.2468 1     0.00   1.2468 1
>>    2 1 5 6 9 180.00  -0.5774 2   180.00  -0.5774 2
>>    2   1   5   6 9   0.00   0.7238 3     0.00   0.7238 3
>>    3   1   5   6 9   0.00   1.2468 1     0.00   1.2468 1
>>    3 1 5 6 9 180.00  -0.5774 2   180.00  -0.5774 2
>>    3   1   5   6 9   0.00   0.7238 3     0.00   0.7238 3
>>    4   1   5   6 9   0.00   1.2468 1     0.00   1.2468 1
>>    4 1 5 6 9 180.00  -0.5774 2   180.00  -0.5774 2
>>    4   1   5   6 9   0.00   0.7238 3     0.00   0.7238 3
>>
>> [ dihedrals ]
>> ; ai aj ak al fu xi0 kxi xi0 kxi
>>    1   2   5   4 2   0.00   0.0000     0.00   0.0000
>>    1   2   5   3 2   0.00   0.0000     0.00   0.0000
>>
>>
>> #ifdef POSRES_LIGAND
>> [ position_restraints ]
>> ; atom  type      fx      fy      fz
>>     1 1 1000 1000 1000
>>     5 1 1000 1000 1000
>> #endif
>>
>>
>> And I included this file in the topology file:
>>
>> #include "charmm27.ff/forcefield.itp"
>>
>> #include "charmm27.ff/nor-antib.itp"
>>
>> #include "charmm27.ff/metanolo.itp"
>>
>> [ system ]
>> ; Name
>> nor
>>
>> [ molecules ]
>> ; Compound        #mols
>> SOL              1000
>> nor-antib        1
>>
>> when I run grompp i get this error:
>>
>> Fatal error:
>> Syntax error - File metanolo.itp, line 7
>> Last line read:
>> '[ atomtypes ]'
>> Invalid order for directive atomtypes
>>
>>
>> What am I doing wrong?? (i use gromacs 5.0.4)
>>
>>
> Please search the archive (I answer this question weekly) and/or visit the
> GROMACS Error page, which discusses this situation/error specifically.
>
> -Justin
>
> --
> ==================================================
>
> Justin A. Lemkul, Ph.D.
> Ruth L. Kirschstein NRSA Postdoctoral Fellow
>
> Department of Pharmaceutical Sciences
> School of Pharmacy
> Health Sciences Facility II, Room 629
> University of Maryland, Baltimore
> 20 Penn St.
> Baltimore, MD 21201
>
> jalemkul at outerbanks.umaryland.edu | (410) 706-7441
> http://mackerell.umaryland.edu/~jalemkul
>
> ==================================================
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