[gmx-users] pdb2gmx error

Mark Abraham mark.j.abraham at gmail.com
Thu Jun 16 13:26:27 CEST 2016


Hi,

Why is your residue numbering and residue naming changing in mutually
inconsistent ways?

Mark

On Thu, Jun 16, 2016 at 9:36 AM bharat gupta <bharat.85.monu at gmail.com>
wrote:

> Hi,
>
> I have been trying to build the toplogy for cellopentoase using the newly
> derived parameters mentioned in this paper:
> http://www.ncbi.nlm.nih.gov/pubmed/21387332. I got the paper from the
> gromacs website:
> http://www.gromacs.org/@api/deki/files/200/=56a_CARBO4GROMACS.rar
>
> When I try to construct the topology file using this forcefield, I am
> getting the following error:
>
> Fatal error:
> Residue 6 named GLCN of a molecule in the input file was mapped
> to an entry in the topology database, but the atom C1 used in
> that entry is not found in the input file. Perhaps your atom
> and/or residue naming needs to be fixed.
>
> I have only 5 residues in the pdb file, but gromacs is counting it as 6
> residues. Here's the pdb file:
>
> HEADER CP5
> ATOM      1  O2  GLC0    1       7.400   0.776  35.278  0.70 24.55
>   O
> ATOM      2  C2  GLC0    1       6.024   0.721  35.632  0.70 23.65
>   C
> ATOM      3  C3  GLC0    1       5.240   0.984  34.354  0.70 21.57
>   C
> ATOM      4  O3  GLC0    1       5.144  -0.245  33.608  0.70 14.59
>   O
> ATOM      5  C4  GLC0    1       3.902   1.571  34.776  0.70 20.91
>   C
> ATOM      6  O4  GLC0    1       3.006   1.662  33.670  0.70 19.67
>   O
> ATOM      7  C5  GLC0    1       4.174   2.944  35.391  0.70 22.32
>   C
> ATOM      8  C6  GLC0    1       2.914   3.605  35.899  0.70 21.51
>   C
> ATOM      9  O6  GLC0    1       2.201   2.690  36.737  0.70 20.09
>   O
> ATOM     10  O5  GLC0    1       5.080   2.890  36.510  0.70 24.12
>   O
> ATOM     11  C1  GLC0    1       5.742   1.651  36.843  0.70 26.75
>   C
> ATOM     12  O1  GLC     1       5.207   0.892  37.971  0.70 30.32
>   O
> ATOM     13  C4  GLC     2       4.222   1.340  38.917  0.70 32.87
>   C
> ATOM     14  C5  GLC     2       4.753   1.239  40.352  0.70 33.51
>   C
> ATOM     15  O5  GLC     2       3.711   1.506  41.306  0.70 35.29
>   O
> ATOM     16  C6  GLC     2       5.888   2.194  40.665  0.70 34.02
>   C
> ATOM     17  O6  GLC     2       5.803   2.537  42.057  0.70 32.97
>   O
> ATOM     18  C3  GLC     2       3.072   0.331  38.851  0.70 33.72
>   C
> ATOM     19  O3  GLC     2       2.435   0.360  37.564  0.70 34.01
>   O
> ATOM     20  C2  GLC     2       2.027   0.450  39.972  0.70 35.29
>   C
> ATOM     21  O2  GLC     2       1.149  -0.684  39.932  0.70 36.32
>   O
> ATOM     22  C1  GLC     2       2.684   0.512  41.351  0.70 36.04
>   C
> ATOM     23  O1  GLC     2       1.704   0.843  42.349  0.70 36.96
>   O
> ATOM     24  C4  GLC     3       2.032   0.454  43.689  0.70 38.12
>   C
> ATOM     25  C5  GLC     3       0.810  -0.195  44.344  0.70 38.87
>   C
> ATOM     26  O5  GLC     3       1.085  -0.507  45.715  0.70 39.40
>   O
> ATOM     27  C6  GLC     3       0.372  -1.455  43.605  0.70 38.87
>   C
> ATOM     28  O6  GLC     3      -0.996  -1.300  43.220  0.70 39.09
>   O
> ATOM     29  C3  GLC     3       2.455   1.683  44.498  0.70 38.55
>   C
> ATOM     30  O3  GLC     3       3.729   2.152  44.043  0.70 38.93
>   O
> ATOM     31  C2  GLC     3       2.550   1.405  45.997  0.70 39.25
>   C
> ATOM     32  O2  GLC     3       2.700   2.646  46.700  0.70 38.44
>   O
> ATOM     33  C1  GLC     3       1.319   0.663  46.514  0.70 39.97
>   C
> ATOM     34  O1  GLC     3       1.522   0.333  47.897  0.70 41.30
>   O
> ATOM     35  C4  GLC     4       0.320  -0.039  48.583  0.70 42.19
>   C
> ATOM     36  C5  GLC     4      -0.067   0.972  49.664  0.70 42.80
>   C
> ATOM     37  O5  GLC     4      -1.358   0.617  50.163  0.70 43.08
>   O
> ATOM     38  C6  GLC     4      -0.082   2.420  49.189  0.70 43.23
>   C
> ATOM     39  O6  GLC     4      -0.900   2.532  48.019  0.70 43.36
>   O
> ATOM     40  C3  GLC     4       0.485  -1.387  49.281  0.70 42.24
>   C
> ATOM     41  O3  GLC     4       0.818  -2.397  48.323  0.70 41.16
>   O
> ATOM     42  C2  GLC     4      -0.782  -1.783  50.046  0.70 42.64
>   C
> ATOM     43  O2  GLC     4      -0.470  -2.862  50.935  0.70 42.32
>   O
> ATOM     44  C1  GLC     4      -1.375  -0.633  50.870  0.70 43.60
>   C
> ATOM     45  O1  GLCN    4      -2.732  -0.947  51.190  0.70 45.14
>   O
> ATOM     46  C4  GLCN    5      -3.137  -0.484  52.482  0.70 46.29
>   C
> ATOM     47  C3  GLCN    5      -4.035   0.750  52.337  0.70 46.70
>   C
> ATOM     48  O3  GLCN    5      -3.269   1.864  51.865  0.70 46.85
>   O
> ATOM     49  C2  GLCN    5      -4.706   1.124  53.659  0.70 47.10
>   C
> ATOM     50  O2  GLCN    5      -5.680   2.147  53.435  0.70 47.17
>   O
> ATOM     51  C1  GLCN    5      -5.377  -0.097  54.282  0.70 47.34
>   C
> ATOM     52  O1  GLCN    5      -5.958   0.264  55.539  0.70 47.48
>   O
> ATOM     53  O5  GLCN    5      -4.397  -1.126  54.467  0.70 47.17
>   O
> ATOM     54  C5  GLCN    5      -3.867  -1.611  53.225  0.70 46.80
>   C
> ATOM     55  C6  GLCN    5      -2.967  -2.814  53.497  0.70 46.93
>   C
> ATOM     56  O6  GLCN    5      -1.934  -2.454  54.421  0.70 47.39
>   O
> END
>
> Can anyone let me know what am I doing wrong?
>
> I am trying to perform MD simulation of protein with cellopentoase. So, in
> order to obtain the parameters for cellopentoase, I am following the
> parameters mentioned above.
>
>
> --
> *Best Regards*
> Bharat
> --
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