[gmx-users] Secondary structure not visible afterconvertingfrom .gro to .pdb

bharat gupta bharat.85.monu at gmail.com
Fri May 30 02:04:23 CEST 2014


Thank Tserjk... This worked successfully...It was really a great help..


On Fri, May 30, 2014 at 4:26 AM, Tsjerk Wassenaar <tsjerkw at gmail.com> wrote:

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> Hey,
>
> The .gro file format has no information about chains, so it won't write any
> when converting to PDB, and Pymol gets mixed up, stopping after the first
> chain. A solution is to use trjconv and a tpr file to convert the .gro file
> to .pdb. The chains will then be set according to the molecules defined in
> the .tpr.
>
> Cheers,
>
> Tsjerk
>
>
> On Thu, May 29, 2014 at 11:33 AM, Erik Marklund <
> erik.marklund at chem.ox.ac.uk
> > wrote:
>
> > Hi,
> >
> > Gromacs sometimes omits chain labels when writing PDBs, so there might
> > actually be something to fix. I don't remember under exactly what
> > circumstances though, and the reason could be perfectly reasonable.
> >
> > Furthermore, in pymol you can assign the secondary structure to a protein
> > in case pymol doesn't do so automatically, which happens e.g. for
> > multi-MODEL structures.
> >
> > Kind regards,
> > Erik
> >
> > On 29 May 2014, at 07:16, Mark Abraham <mark.j.abraham at gmail.com> wrote:
> >
> > > It seems like you've generated a structure that does not match the
> > > preconceptions of PyMol. What is there to solve?
> > >
> > > Mark
> > > On May 29, 2014 8:09 AM, "bharat gupta" <bharat.85.monu at gmail.com>
> > wrote:
> > >
> > >> Sorry, it was my mistake actually i opened this file in excel that's
> > why I
> > >> got that kind of numbering.
> > >>
> > >> But still, whats the solution to my problem. I will post this query in
> > >> Pymol mailing list also.
> > >>
> > >>
> > >> On Thu, May 29, 2014 at 2:56 PM, Mark Abraham <
> mark.j.abraham at gmail.com
> > >>> wrote:
> > >>
> > >>> Hi,
> > >>>
> > >>> That seems like a bug. What GROMACS command and version produced it?
> > >>>
> > >>> Mark
> > >>> On May 29, 2014 6:40 AM, "bharat gupta" <bharat.85.monu at gmail.com>
> > >> wrote:
> > >>>
> > >>>> Thanks you all for your responses. As far the chain name is
> concerned,
> > >>> that
> > >>>> can be worked out by a simple script. But I found another issue in
> the
> > >>>> converted pdb file that gromacs gives some weird numbering after
> atom
> > >>>> 99999. Here's the sample from the converted pdb file :-
> > >>>>
> > >>>> ATOM  99999  HA  ALA X 609     145.370 109.310  33.980  0.00  0.00
> > >>>>
> > >>>> ATOM  186a0  CB  ALA X 609     144.460 108.520  35.770  0.00  0.00
> > >>>>
> > >>>> ATOM  186a1  HB1 ALA X 609     143.430 108.800  35.570  0.00  0.00
> > >>>>
> > >>>> ATOM  186a2  HB2 ALA X 609     144.600 107.490  35.440  0.00  0.00
> > >>>>
> > >>>> ATOM  186a3  HB3 ALA X 609     144.590 108.530  36.850  0.00  0.00
> > >>>>
> > >>>> ATOM  186a4  C   ALA X 609     145.090 110.890  35.400  0.00  0.00
> > >>>>
> > >>>> ATOM  186a5  O   ALA X 609     144.400 111.540  34.620  0.00  0.00
> > >>>>
> > >>>> ATOM  186a6  N   PHE X 610     145.520 111.380  36.560  0.00  0.00
> > >>>>
> > >>>> ATOM  186a7  H   PHE X 610     146.110 110.800  37.130  0.00  0.00
> > >>>>
> > >>>> ATOM  186a8  CA  PHE X 610     145.120 112.700  37.050  0.00  0.00
> > >>>>
> > >>>> ATOM  186a9  HA  PHE X 610     144.160 113.010  36.630  0.00  0.00
> > >>>>
> > >>>> ATOM  186aa  CB  PHE X 610     145.000 112.640  38.580  0.00  0.00
> > >>>>
> > >>>> ATOM  186ab  HB1 PHE X 610     145.860 112.140  39.030  0.00  0.00
> > >>>>
> > >>>> ATOM  186ac  HB2 PHE X 610     145.010 113.650  38.970  0.00  0.00
> > >>>>
> > >>>> ATOM  186ad  CG  PHE X 610     143.710 112.010  39.090  0.00  0.00
> > >>>>
> > >>>> ATOM  186ae  CD1 PHE X 610     142.590 112.820  39.360  0.00  0.00
> > >>>>
> > >>>> ATOM  186af  HD1 PHE X 610     142.620 113.880  39.170  0.00  0.00
> > >>>>
> > >>>> ATOM  186b0  CD2 PHE X 610     143.630 110.610  39.300  0.00  0.00
> > >>>>
> > >>>> ATOM  186b1  HD2 PHE X 610     144.480 109.980  39.090  0.00  0.00
> > >>>>
> > >>>> ATOM  186b2  CE1 PHE X 610     141.400 112.240  39.840  0.00  0.00
> > >>>>
> > >>>> ATOM  186b3  HE1 PHE X 610     140.540 112.860  40.040  0.00  0.00
> > >>>>
> > >>>> ATOM  186b4  CE2 PHE X 610     142.440 110.040  39.780  0.00  0.00
> > >>>>
> > >>>> ATOM  186b5  HE2 PHE X 610     142.380 108.970  39.940  0.00  0.00
> > >>>>
> > >>>> ATOM  186b6  CZ  PHE X 610     141.330 110.860  40.060  0.00  0.00
> > >>>>
> > >>>> ATOM  186b7  HZ  PHE X 610     140.410 110.430  40.430  0.00  0.00
> > >>>>
> > >>>> ATOM  186b8  C   PHE X 610     146.160 113.780  36.700  0.00  0.00
> > >>>>
> > >>>> ATOM  186b9  O   PHE X 610     145.840 114.970  36.770  0.00  0.00
> > >>>>
> > >>>> ATOM  186ba  N   GLU X 611     147.400 113.400  36.350  0.00  0.00
> > >>>>
> > >>>> ATOM  186bb  H   GLU X 611     147.610 112.410  36.340  0.00  0.00
> > >>>>
> > >>>> ATOM  186bc  CA  GLU X 611     148.490 114.340  36.120  0.00  0.00
> > >>>>
> > >>>> ATOM  186bd  HA  GLU X 611     148.460 115.100  36.900  0.00  0.00
> > >>>>
> > >>>> ATOM  186be  CB  GLU X 611     149.840 113.580  36.110  0.00  0.00
> > >>>>
> > >>>> ATOM  186bf  HB1 GLU X 611     149.720 112.590  35.680  0.00  0.00
> > >>>>
> > >>>> ATOM  186c0  HB2 GLU X 611     150.560 114.090  35.470  0.00  0.00
> > >>>>
> > >>>> ATOM  186c1  CG  GLU X 611     150.480 113.460  37.510  0.00  0.00
> > >>>>
> > >>>> ATOM  186c2  HG1 GLU X 611     149.840 112.900  38.170  0.00  0.00
> > >>>>
> > >>>> ATOM  186c3  HG2 GLU X 611     151.410 112.910  37.430  0.00  0.00
> > >>>>
> > >>>> ATOM  186c4  CD  GLU X 611     150.780 114.810  38.130  0.00  0.00
> > >>>>
> > >>>> ATOM  186c5  OE1 GLU X 611     150.020 115.240  39.030  0.00  0.00
> > >>>>
> > >>>> ATOM  186c6  OE2 GLU X 611     151.720 115.490  37.650  0.00  0.00
> > >>>>
> > >>>> ATOM  186c7  C   GLU X 611     148.340 115.110  34.790  0.00  0.00
> > >>>>
> > >>>> ATOM  186c8  O   GLU X 611     148.850 116.220  34.680  0.00  0.00
> > >>>>
> > >>>> ATOM  186c9  N   VAL X 612     147.610 114.560  33.820  0.00  0.00
> > >>>>
> > >>>>
> > >>>> On Thu, May 29, 2014 at 12:58 PM, Christopher Neale <
> > >>>> chris.neale at alum.utoronto.ca> wrote:
> > >>>>
> > >>>>> [image: Boxbe] <https://www.boxbe.com/overview> This message is
> > >>>> eligible
> > >>>>> for Automatic Cleanup! (chris.neale at alum.utoronto.ca) Add cleanup
> > >>> rule<
> > >>>>
> > >>>
> > >>
> >
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> > >>>> |
> > >>>> More
> > >>>>> info<
> > >>>>
> > >>>
> > >>
> >
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> > >>>>>
> > >>>>>
> > >>>>> Sounds reasonable now. If 10 molecules are all listed as part of
> the
> > >>> same
> > >>>>> chain (PDB format) then maybe Pymol will stop rendering after the
> > >> first
> > >>>>> "chain". So either script changing the chain info or find some
> other
> > >>> way
> > >>>> to
> > >>>>> have them listed as different chains in the .pdb or (perhaps) just
> > >> use
> > >>> a
> > >>>>> .gro -- if pymol will work with this -- since AFAIK a .gro file
> does
> > >>> not
> > >>>>> list chains so Pymol may be forced to figure things out on its own.
> > >>>>>
> > >>>>> At this point, it does really seem like a Pymol issue, so I agree
> > >> with
> > >>>>> previous posters that you will get the most useful help on a Pymol
> > >>>> mailing
> > >>>>> list.
> > >>>>>
> > >>>>> Chris.
> > >>>>> ________________________________________
> > >>>>> From: gromacs.org_gmx-users-bounces at maillist.sys.kth.se <
> > >>>>> gromacs.org_gmx-users-bounces at maillist.sys.kth.se> on behalf of
> > >> bharat
> > >>>>> gupta <bharat.85.monu at gmail.com>
> > >>>>> Sent: 28 May 2014 21:24
> > >>>>> To: Discussion list for GROMACS users
> > >>>>> Subject: Re: [gmx-users] Secondary structure not visible after
> > >>> converting
> > >>>>>      from .gro to .pdb
> > >>>>>
> > >>>>> Hi,
> > >>>>>
> > >>>>> I energy minimized a protein consisting 10 chains using gromacs.
> > >> When I
> > >>>>> converted the structure of the protein from gro format to pdb
> format
> > >> to
> > >>>>> visualize in Pymol, it shows only one chain in ribbon form and rest
> > >> of
> > >>>> the
> > >>>>> chains are not shown ... How to rectify this error ??
> > >>>>>
> > >>>>>
> > >>>>> Regards
> > >>>>> -----
> > >>>>> Bharat
> > >>>>> --
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> --
> Tsjerk A. Wassenaar, Ph.D.
> --
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